The most common piece of feedback we get from people taking Clarity is that their sleep has improved. Anecdotal reports are great but what does the science say?
There are studies that have demonstrated that low dose actually has a stimulating effect while high dose has the opposite effect and acts as a sedative. The main issue with these studies is that they are looking at in combination with THC and not it alone.
What looks likely is that, most of the time, difficulty sleeping is the result of another condition like mild anxiety or pain. Research suggests that it can be used to treat both anxiety and pain and this may lead to improved sleep.
One recent study from 2019 concluded that it shows promise as a tool for reducing anxiety at doses of 25mg. The study involved 72 subjects, 47 with anxiety and 25 with poor sleep. The participants were each given 25mg in capsule form once daily. In the first month, 79% of the patients reported lower anxiety levels and 66% reported better sleep.
Another study investigating the short‐term effect for relieving pain symptoms and improving the quality of life showed that, compared to baseline, there were significant reductions in pain scores. Although not the primary focus of the study, the researchers reported that sleep disorders are a common symptom in all the participants who usually slept 3 hours or less a night. This was significantly alleviated in the first month of treatment, with all the participants sleeping 6–8 hours a night.
A study from 2018 examined the impact of a single dose on the sleep wake cycle of healthy subjects and showed no significant difference between it and placebo. In this study, patients were given 300mg orally one night and placebo the next. This result is interesting as a lot of the feedback we are seeing is that people using start to experience a benefit after making it part of a daily routine but not necessarily the first time they use it.
The literature is confusing for a number of reasons. Dosage and protocols between studies vary and many studies involve examination together making it impossible to determine the effects of these compounds in isolation. To confuse things even more, impact on sleep is often something that is observed but is not the primary focus of the study.